Supplement × Supplement·a synergy·Emerging evidence
FOS fermentation may improve calcium solubility and absorption in the colon in some contexts.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. FOS fermentation may improve calcium solubility and absorption in the colon in some contexts.
Mechanism. SCFA production lowers colonic pH and can increase mineral solubility.
Recommendation. Can be part of a bone-health diet, but do not use FOS as a substitute for adequate calcium and vitamin D.
Effect on the composite score
If both Calcium and Fructooligosaccharides (FOS) are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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