From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyModerate evidence
What is happening. FOS can act as a prebiotic substrate for probiotic organisms and resident bifidobacteria.
Mechanism. Prebiotic fermentation supports bacterial growth and SCFA production.
Recommendation. Start low and titrate one product at a time to reduce gas.
Stack Score
How it moves the number.
Effect on the composite score
If both Fructooligosaccharides (FOS) and Probiotics are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Holscher HD et al. Inulin-type fructans systematic review. Nutrients. 2021.Needs sourceNo link