NutriStack
GABA and L-Theanine, a synergy.
Complementary calming effect, with L-theanine promoting relaxed alertness and increasing alpha brain-wave activity alongside GABA's inhibitory signaling.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- GABA and L-Theanine
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Complementary calming effect, with L-theanine promoting relaxed alertness and increasing alpha brain-wave activity alongside GABA's inhibitory signaling.
Mechanism. L-theanine modulates glutamate and GABA neurotransmission and raises alpha-wave activity, while supplemental GABA may act on peripheral and enteric GABA receptors; together they promote a calm state through complementary pathways.
Recommendation. Reasonable to combine for relaxation or sleep onset; start low and assess your own response. No timing separation needed.
Sources (2)
Stack Score
How this pair moves the number.
Effect on the composite score
If both GABA and L-Theanine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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