From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyModerate evidence
What is happening. GOS can feed bifidobacteria and may complement probiotic supplements.
Mechanism. Prebiotic oligosaccharides selectively support bifidobacterial fermentation.
Recommendation. Start low and titrate one product at a time to limit gas.
Stack Score
How it moves the number.
Effect on the composite score
If both Galactooligosaccharides (GOS) and Probiotics are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Silk DBA et al. Trans-galactooligosaccharide prebiotic in IBS. Alimentary Pharmacology & Therapeutics. 2009.Needs sourceNo link