From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Supplement
Last verified
June 4, 2026
Timing SensitiveEmerging evidence
What is happening. Soluble fiber can reduce or delay mineral supplement absorption when taken at the same time.
Mechanism. Fiber matrix can bind or slow contact between minerals and absorptive surfaces.
Recommendation. Separate iron from PHGG by at least 2 hours when treating iron deficiency.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Iron and Partially Hydrolyzed Guar Gum (Sunfiber) are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Parisi GC et al. PHGG versus placebo in IBS. Turkish Journal of Gastroenterology. 2016.Needs sourceNo link