Supplement × Supplement·a synergy·Moderate evidence
Vitamin D status influences endogenous cathelicidin expression, but this does not validate exogenous LL-37 use.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Vitamin D status influences endogenous cathelicidin expression, but this does not validate exogenous LL-37 use.
Mechanism. Vitamin D regulation of innate antimicrobial peptide pathways.
Recommendation. Correct vitamin D deficiency through standard care rather than using LL-37 products.
Effect on the composite score
If both LL-37 and Vitamin D3 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
NutriStack