NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Plant Sterols (Phytosterols) and Vitamin E: what the published research says

PubMed indexes 3 records that name Plant Sterols (Phytosterols) and Vitamin E together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Plant Sterols (Phytosterols) and Vitamin E. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

3 studies naming Plant Sterols (Phytosterols) and Vitamin E.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Effects on the human serum lipoprotein profile of beta-glucan, soy protein and isoflavones, plant sterols and stanols, garlic and tocotrienols.

The Journal of nutrition · 2002 · PMID 12221200

ReviewHuman subjects

“It is important to characterize the active components in garlic and their bioavailability after ingestion. It is not very likely that tocotrienols from palm oil or rice bran oil have favorable effects on the human serum lipoprotein profile.”

Kerckhoffs et al. · From the abstract

Names both Plant Sterols (Phytosterols) and Vitamin E in its title.

Plasma fat-soluble vitamin and carotenoid concentrations after plant sterol and plant stanol consumption: a meta-analysis of randomized controlled trials.

European journal of nutrition · 2017 · PMID 27591863

Meta-AnalysisReviewHuman subjects

“Plant sterol and stanol intake lowers TC-standardized hydrocarbon carotenoid concentrations, differently affects TC-standardized oxygenated carotenoid concentrations, but does not affect TC-standardized tocopherol concentrations or absolute retinol and vitamin D concentrations. Observed concentrations remained within normal ranges.”

Baumgartner et al. · Authors' conclusion

Names Plant Sterols (Phytosterols) and Vitamin E together in an interaction, co-administration, or pharmacokinetic context.

Experimental pasta as an innovative approach to cholesterol reduction in patients with metabolic syndrome, with and without major psychiatric disorders: A randomized controlled trial supported by in vitro validation.

European psychiatry : the journal of the Association of European Psychiatrists · 2025 · PMID 40620194

Randomized Controlled Trial

“These results indicate that a low-impact lifestyle intervention may offer a practical strategy for improving the cholesterol profile and mitigating cardiovascular risk in patients with MetS, with and without an MPD.”

D'Ambrosio et al. · Authors' conclusion

Names Plant Sterols (Phytosterols) and Vitamin E together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Plant Sterols (Phytosterols), Vitamin E, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.