From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Supplement
Last verified
June 4, 2026
Timing SensitiveModerate evidence
What is happening. Plant sterols can reduce absorption of some fat-soluble compounds and carotenoids.
Mechanism. Competition within intestinal micelles can reduce fat-soluble nutrient absorption.
Recommendation. Take vitamin E at a different meal if deficiency treatment is needed, and maintain a fruit/vegetable-rich diet.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Plant Sterols (Phytosterols) and Vitamin E are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Demonty I et al. Sterol/stanol capsule meta-analysis. Journal of the Academy of Nutrition and Dietetics. 2013.Needs sourceNo link