Supplement × Supplement·timing-sensitive·Moderate evidence

Plant Sterols (Phytosterols) + Vitamin E

Timing Sensitive Moderate evidence

Plant sterols can reduce absorption of some fat-soluble compounds and carotenoids.

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Pair type
Timing Sensitive
Evidence
Moderate
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
Timing SensitiveModerate evidence

What is happening. Plant sterols can reduce absorption of some fat-soluble compounds and carotenoids.

Mechanism. Competition within intestinal micelles can reduce fat-soluble nutrient absorption.

Recommendation. Take vitamin E at a different meal if deficiency treatment is needed, and maintain a fruit/vegetable-rich diet.

Timing

Timing & separation.

Space the doses apart by at least this window to avoid the conflict.

Minimum separation
120
Stack Score

How it moves the number.

Effect on the composite score

If both Plant Sterols (Phytosterols) and Vitamin E are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1Demonty I et al. Sterol/stanol capsule meta-analysis. Journal of the Academy of Nutrition and Dietetics. 2013.Needs sourceNo link

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