Interaction databaseSupplement × SupplementReviewed May 2026

Quercetin and Zinc, a synergy.

Quercetin has shown zinc-ionophore activity in cell models, but clinical immune benefit from combining quercetin with zinc is not established.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

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From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Quercetin and Zinc
Pair type
Synergy
Evidence (highest tier)
Emerging
Source citations
1 source
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Emerging evidence

Synergy

What is happening. Quercetin has shown zinc-ionophore activity in cell models, but clinical immune benefit from combining quercetin with zinc is not established.

Mechanism. Cell studies suggest quercetin can transport zinc across membranes. Translation to meaningful antiviral or immune outcomes in humans has not been established.

Recommendation. Do not rely on quercetin plus zinc as antiviral treatment. Use only as general nutrition support and keep zinc within standard supplemental limits unless clinician-directed.

Sources (1)
  1. Dabbagh-Bazarbachi H et al. Zinc ionophore activity of quercetin and epigallocatechin-gallate. J Agric Food Chem. 2014;62(32):8085-8093. PMID 25050823

Stack Score

How this pair moves the number.

Effect on the composite score

If both Quercetin and Zinc are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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