What supplements are associated with irregular menstrual cycles?

In the NutriStack library, the supplements most associated with irregular menstrual cycles are Inositol, Vitamin D3, Iron, Magnesium Glycinate, Vitamin B6. Each is ranked by relevance and by its own evidence rating, and links to a full profile with dosing, forms, and PubMed-cited sources.

How are supplements ranked for irregular menstrual cycles?

Matches are ordered by a relevance score that reflects how directly each supplement targets the symptom, then by the supplement's evidence tier. Full methodology is at https://nutristackapp.com/methodology.

Symptom·Hormone·Reviewed May 30, 2026

Supplements for Irregular menstrual cycles.

When irregular menstrual cycles is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.

Matches7 supplements Strong evidence0 of 7 Last reviewedMay 30, 2026

Supplements

Ranked by relevance, top first.

Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.

01
InositolModerate
86% match
Myo-inositol can improve insulin signaling and ovarian function, which may help restore ovulation and cycle regularity in PCOS-related irregularity.
SuggestedMyo-inositol plus D-chiro-inositol in a 40:1 ratio
02
Vitamin D3Limited
72% match
Vitamin D receptors are present in ovarian tissue, and correcting deficiency is associated with more regular cycles in some PCOS studies.
SuggestedD3 (cholecalciferol) softgels
03
IronModerate
68% match
Iron deficiency can disrupt the hypothalamic-pituitary axis, and is both a possible cause and a consequence of abnormal menstrual bleeding.
SuggestedIron bisglycinate
04
Magnesium GlycinateLimited
62% match
Magnesium supports stress-hormone regulation and insulin sensitivity, which may indirectly influence cycle stability.
SuggestedMagnesium glycinate capsules
05
Vitamin B6Limited
60% match
Vitamin B6 supports luteal-phase function and dopamine balance, which may help when irregularity overlaps with high prolactin or PMS.
SuggestedPyridoxal-5-phosphate (P5P) capsules
06
Maca RootLimited
56% match
Maca is traditionally used to support hormonal balance and may influence cycle regularity, but controlled human evidence is limited.
SuggestedGelatinized maca root powder or capsules
07
DIMLimited
55% match
DIM (diindolylmethane) influences estrogen metabolism, which is sometimes targeted in estrogen-dominant irregularity, though clinical data are preliminary.
SuggestedDiindolylmethane (DIM) capsules, often with BioPerine

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Supplements for Irregular menstrual cycles.

Ranked by relevance, top first.

Related symptoms.

Every match traces to a full profile.