NutriStack
Symptom·Hormone·Reviewed May 30, 2026
Supplements for Menstrual (hormonal) migraine.
When menstrual (hormonal) migraine is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Magnesium GlycinateModerate92% match
Magnesium stabilizes neuronal excitability and vascular tone, and low levels are common in people whose migraines cluster around the estrogen drop before menstruation.
Suggested300 to 400 mg elemental magnesium daily, ideally started a few days before the expected period and continued through the bleed - 02Vitamin B2Moderate85% match
Riboflavin supports mitochondrial energy metabolism in neurons, a pathway implicated in migraine susceptibility, and has reduced migraine frequency in trials.
Suggested400 mg riboflavin once daily as ongoing prophylaxis - 03Coenzyme Q10Limited78% match
CoQ10 aids mitochondrial ATP production and has reduced migraine days in randomized trials, complementing the same energy-deficit model as riboflavin.
Suggested100 mg three times daily (300 mg per day) with food for absorption - 04Fish OilLimited62% match
Omega-3 EPA and DHA lower prostaglandin-driven inflammation, which is elevated perimenstrually and contributes to both cramps and headache.
Suggested1 to 2 g combined EPA and DHA daily with meals - 05Vitamin B6Limited50% match
Vitamin B6 supports neurotransmitter synthesis and may ease the late-luteal hormonal symptom burden that accompanies menstrual migraine in some people.
Suggested25 to 50 mg daily during the second half of the cycle
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