From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Supplement
Last verified
June 4, 2026
Timing SensitiveModerate evidence
What is happening. High-dose zinc can lower copper status; systemic copper peptide use can make copper-zinc interpretation harder.
Mechanism. Copper-zinc competitive balance.
Recommendation. Avoid high-dose zinc unless indicated; monitor copper and zinc if systemic exposure occurs.
Stack Score
How it moves the number.
Effect on the composite score
If both GHK-Cu (Copper Peptide) and Zinc are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Pickart L et al. GHK-Cu regenerative actions review. Int J Mol Sci. 2018.Needs sourceNo link