NutriStack
Selenium and Zinc, a synergy.
Both support immune function and antioxidant defense. Zinc supports SOD and thymulin; selenium supports GPx and selenoproteins.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Both support immune function and antioxidant defense. Zinc supports SOD and thymulin; selenium supports GPx and selenoproteins.
Mechanism. Zinc activates Cu/Zn-SOD, supports thymic function, and is needed for T-cell proliferation. Selenium supports glutathione peroxidases and thioredoxin reductases. Complementary immune-antioxidant pathways.
Recommendation. Take together for comprehensive immune and antioxidant support.
Sources (1)
- Calder PC et al. Optimal nutritional status for a well-functioning immune system. Nutrients. 2020
Stack Score
How this pair moves the number.
Effect on the composite score
If both Selenium and Zinc are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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