Supplement × Supplement·Evidence index
PubMed indexes 8 records that name Selenium and Zinc together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Selenium and Zinc. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
“The intervention duration ranged from 2 weeks to 18 months. Conclusion: In the present study, we identified some clinical evidence of a potential beneficial effect of selenium supplementation in HIV-infected patients.”
Names both Selenium and Zinc in its title.
“Serum Cu levels ≥99.48 μg/dL are significantly linked to diabetes risk, while serum Se levels ≥122.74 μg/L are associated with diabetes risk and levels <157.56 μg/L with elevated heart attack risk. Serum metal mixtures containing Cu, Se and Zn were significantly and positively associated with risk of diabetes, hypertension and heart attack.”
Names both Selenium and Zinc in its title.
Names both Selenium and Zinc in its title.
“Consequently, these three elements offer promise as practical, accessible biomarkers for the early identification and risk stratification of individuals susceptible to cognitive impairment. Future research should prioritize clinical trials focused on targeted nutritional strategies-specifically optimizing dietary intake and/or supplementation of selenium and zinc while carefully managing copper balance-as a viable primary prevention approach to reduce the global burden of…”
Names both Selenium and Zinc in its title.
Names both Selenium and Zinc in its title.
“Currently, serum zinc and selenium deficiencies increase the incidence of COVID-19 and zinc deficiency exacerbates the disease; however, neither zinc nor selenium was associated with mortality in patients with COVID-19. Nevertheless, our conclusions may change when new clinical studies are published.”
Names both Selenium and Zinc in its title.
“There was an interaction between dietary selenium and zinc intakes on the risk of new-onset hypothyroidism, especially the significant effect for adults with women or overweight. The findings indicated that improving the levels of dietary zinc and selenium intake may be beneficial in preventing of new-onset hypothyroidism.”
Names both Selenium and Zinc in its title.
Names both Selenium and Zinc in its title.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Selenium, Zinc, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
