NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Jujube and Melatonin: what the published research says

PubMed indexes 4 records that name Jujube and Melatonin together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Jujube and Melatonin. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

4 studies naming Jujube and Melatonin.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Melatonin activates the ZjERF34-ZjMYB1 regulatory pathway to promote flavonoid biosynthesis and salt tolerance in jujube (Ziziphus jujuba Mill.).

BMC plant biology · 2026 · PMID 42286505

“Collectively, our findings reveal a MT-ZjERF34-ZjMYB1-ZjF3H/FLS regulatory module that links hormonal signaling with flavonoid biosynthesis and abiotic stress responses, providing new insights and potential molecular targets for improving fruit quality and stress resilience in horticultural crops.”

Wen et al. · Authors' conclusion

Names both Jujube and Melatonin in its title.

Effects of four disease-controlling agents (chlorothalonil, CuCl(2), harpin, and melatonin) on postharvest jujube fruit quality.

Scientific reports · 2023 · PMID 37217535

“Moreover, treatment with CuCl2 also increased copper accumulation ~ threefold in postharvest jujube fruit. Among the four agents, postharvest treatment with CuCl2 could be considered most appropriate for improving postharvest jujube fruit quality under low temperature conditions without sterilization.”

Tian et al. · From the abstract

Names both Jujube and Melatonin in its title.

Exogenous melatonin treatment on post-harvest jujube fruits maintains physicochemical qualities during extended cold storage.

PeerJ · 2022 · PMID 36262410

“In addition, jujube fruits soaked with melatonin showed improved antioxidant capacity through increased ascorbic acid (AsA) content, enhanced superoxide dismutase (SOD) activity, and decreased malonaldehyde (MDA) content. As a result, 50 µM melatonin showed the greatest improvement of visual appearance and quality maintenance, and could be used as an effective treatment to preserve postharvest jujube fruit.”

Wang et al. · From the abstract

Names both Jujube and Melatonin in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Jujube, Melatonin, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.