Resveratrol and Turmeric/Curcumin, a caution.
Both polyphenols have antiplatelet activity, so combining them may additively reduce platelet aggregation and increase bleeding tendency.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Resveratrol and Turmeric/Curcumin
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Both polyphenols have antiplatelet activity, so combining them may additively reduce platelet aggregation and increase bleeding tendency.
Mechanism. Curcumin and resveratrol each inhibit platelet aggregation, in part through modulation of the arachidonic acid and thromboxane A2 pathway, so their combined antiplatelet effects can be additive.
Recommendation. Generally safe together at supplemental doses, but use caution if you take anticoagulant or antiplatelet drugs, and stop both about 1 to 2 weeks before surgery.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Resveratrol and Turmeric/Curcumin are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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