NutriStack
Symptom·Cardiometabolic·Reviewed May 30, 2026
Supplements for Poor vascular / endothelial function (nitric oxide support).
When poor vascular / endothelial function (nitric oxide support) is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01L-CitrullineModerate82% match
L-citrulline raises plasma arginine and nitric oxide more reliably than arginine itself, improving endothelium-dependent vasodilation.
SuggestedL-citrulline or citrulline malate powder - 02Fish OilModerate72% match
Omega-3 fatty acids improve endothelial function and arterial flexibility and reduce vascular inflammation.
SuggestedEPA and DHA triglyceride-form fish oil - 03Pine Bark ExtractLimited66% match
Pycnogenol increases endothelial nitric oxide synthase activity and has improved flow-mediated dilation in trials.
SuggestedStandardized pine bark extract (Pycnogenol) - 04L-ArginineModerate62% match
Arginine is the direct substrate for nitric oxide synthesis, supporting vasodilation when endothelial function is impaired.
SuggestedL-arginine, divided doses - 05Grape Seed ExtractLimited55% match
Its proanthocyanidins enhance nitric oxide availability and antioxidant defense in the vessel wall.
SuggestedStandardized grape seed proanthocyanidin extract - 06ResveratrolLimited50% match
Resveratrol upregulates endothelial nitric oxide synthase and has acutely improved flow-mediated dilation in some studies.
SuggestedTrans-resveratrol
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