Supplement × Prescription·a synergy·Moderate evidence
Tenofovir disoproxil can reduce bone mineral density and may contribute to phosphate wasting; correcting vitamin D deficiency is part of bone-risk management.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Tenofovir disoproxil can reduce bone mineral density and may contribute to phosphate wasting; correcting vitamin D deficiency is part of bone-risk management.
Mechanism. Bone-risk mitigation rather than increased antiviral exposure.
Recommendation. Check 25-hydroxyvitamin D and bone risk when therapy is long term or risk factors are present; supplement to target if deficient.
Effect on the composite score
If both Tenofovir Disoproxil and Vitamin D3 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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