NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Alcohol and Amphetamine/Dextroamphetamine: what the published research says

PubMed indexes 4 records that name Alcohol and Amphetamine/Dextroamphetamine together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Alcohol and Amphetamine/Dextroamphetamine. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

4 studies naming Alcohol and Amphetamine/Dextroamphetamine.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Co-abuse of amphetamine and alcohol harms kidney and liver.

Scientific reports · 2024 · PMID 39379507

Human subjects

“Study reveals synergistic liver and kidney toxicity. Amphetamine-alcohol co-abuse significantly heightens kidney and liver toxicity.”

Alharbi et al. · From the abstract

Names both Alcohol and Amphetamine/Dextroamphetamine in its title.

Alcohol withdrawal and amphetamine co-use in an animal model for attention deficit hyperactivity disorder.

The American journal of drug and alcohol abuse · 2024 · PMID 38833614

Animal study

“However, as a model for ADHD, SHR adolescents appeared resistant to developing significant signs of alcohol withdrawal following alcohol consumption. Whether alcohol withdrawal symptoms are attenuated or absent, potential consequences could include a decreased awareness of an emerging problem with alcohol use.”

Shah et al. · From the abstract

Names both Alcohol and Amphetamine/Dextroamphetamine in its title.

Alcohol, cannabis and amphetamine-type stimulants use among young Pacific Islanders.

Drug and alcohol review · 2011 · PMID 21219505

ReviewHuman subjects

“There appear to be evidence of risky alcohol consumption and higher levels of cannabis and amphetamine-type stimulants use in some PICTs compared with Australia and New Zealand. However, data are generally unavailable to establish any trends. Regular, reliable and routine monitoring of patterns and trends in substance use among young people in the PICTs can assist in identifying concerns and developing evidence-informed interventions to prevent, contain and treat current and…”

Howard et al. · Authors' conclusion

Names both Alcohol and Amphetamine/Dextroamphetamine in its title.

Methamphetamine and ethanol interactions in humans.

Clinical pharmacology and therapeutics · 1995 · PMID 7768079

Clinical TrialComparative StudyControlled Clinical Trial

“As a potent sympathomimetic drug with alpha-agonist-like effects, methamphetamine increased systolic blood pressure, with minimal change in heart rate. The concurrent administration of methamphetamine and ethanol increased cardiac work, which could produce more adverse cardiovascular effects than either drug taken alone. The increased perceived global intoxication may explain the popularity of this drug combination.”

Mendelson et al. · Authors' conclusion

Names Alcohol and Amphetamine/Dextroamphetamine together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Alcohol, Amphetamine/Dextroamphetamine, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.